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Creation date: 2024-10-15
Creation time: 15-45-02
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8
article
31
Electroconvulsive therapy for psychosis in a patient with epilepsy related to hypothalamic hamartoma
Epileptic Disord
2013
9
15
3
347-351
Psychosis is more common in people with temporal lobe epilepsy than it is in the general population. Treatment can be difficult in these patients because of the complex interactions between antipsychotic and antiepileptic drugs. Some antipsychotic drugs also decrease the seizure threshold. We report the case of a 49-year-old man with a hypothalamic hamartoma, with a history of both gelastic and temporal lobe seizures. The patient was rendered seizure-free after three neurosurgical procedures but developed a drug-resistant paranoid psychosis. He was treated with electroconvulsive therapy (ECT). After two weeks with six stimulations that resulted in seizures, the psychiatric phenomena disappeared completely. There was no relapse of either the psychiatric symptoms or the seizures during the 42 months of follow-up. This case report suggests that ECT might be safe for psychosis in patients with a history of seizures that have previously been successfully treated with neurosurgery, although caution should be exercised in drawing general conclusions from a single case report.
http://www.ncbi.nlm.nih.gov/pubmed/23899761
ElisabethRuppert
LaurenceLalanne
Jack RFoucher
Marie-AgatheZimmermann
EdouardHirsch
PierreVidailhet
article
29
A custom robot for Transcranial Magnetic Stimulation: First assessment on healthy subjects
Conf Proc IEEE Eng Med Biol Soc
2013
5352-5
In this paper, a custom robotic system for Transcranial Magnetic Stimulation is assessed in clinical conditions on healthy subjects. A motor cortex mapping is performed using the robotic system with comparison to a manual approach using a neuronavigation system. Stimulation accuracy, repeatability are evaluated as well as the feeling of the system operator and the subject in terms of comfort, tiredness, stress level, ease-of-use. Very encouraging results are obtained on all these aspects, which strengthens the idea of developing robotic assistance for TMS.
validation
http://www.axilumrobotics.com/pdf/A_Custom_Robot_for_Transcranial_Magnetic_Stimulation_First-EMBC2013.pdf
http://www.ncbi.nlm.nih.gov/pubmed/24110945
RomualdGinhoux
PierreRenaud
LucileZorn
LaurentGoffin
BernardBayle
Jack RFoucher
JulienLamy
Jean-PaulArmspach
Michelde Mathelin
article
26
Design and evaluation of a robotic system for transcranial magnetic stimulation
IEEE Trans Biomed Eng
2012
59
805-815
Transcranial magnetic stimulation is a noninvasive brain stimulation technique. It is based on current induction in the brain with a stimulation coil emitting a strong varying magnetic field. Its development is currently limited by the lack of accuracy and repeatability of manual coil positioning. A dedicated robotic system is proposed in this paper. Contrary to previous approaches in the field, a custom design is introduced to maximize the safety of the subject. Furthermore, the control of the force applied by the coil on the subject's head is implemented. The architecture is original and its experimental evaluation demonstrates its interest: the compensation of the head motion is combined with the force control to ensure accuracy and safety during the stimulation.
validation
http://www.ncbi.nlm.nih.gov/pubmed/22186930
LucileZorn
PierreRenaud
BernardBayle
LaurentGoffin
CyrilleLebossé
Michelde Mathelin
Jack RFoucher
poster
901
Robotic assistance in coil positioning improves reliability and comfort
2012
In the context of personalized rTMS treatment, coil positioning and monitoring is crucial. Moving it from laboratory to hard working clinical setting might be too much burden for human operators. Robotic assistance could preserve precision without fatigue and a single person could manage several devices. We measured the gain of robotic assistance vs neuro-navigated manual coil placement during MEP mapping in terms of reliability, duration, manipulator and participant feeling.
validation
http://www.axilumrobotics.com/pdf/Poster_TMS-Robot-0_Berlin_DGHS_2012-06-14.pdf
Berlin, Germany
German Society for Brain Stimulation
21-22th of june 2012
Jack RFoucher
KevinLorgouilloux
JirkaTurek
Bich-ThuyPham
JulienElowe
BernardBayle
PierreRenaud
LaurentGoffin
LucileZorn
Michelde Mathelin
RomualdGinhoux
BenjaminMaurin
JulienLamy
Jean-PaulArmspach
inbook
401
Imagerie et neuronavigation
2009
http://superieur.deboeck.com/titres/127914_2_0/stimulation-magnetique-transcranienne-principes-et-applications-en-psychiatrie.html
Brunelin J, Galinowski A, Januel D et Poulet E
Solal
Stimulation Magnétique Transcrânienne : Principes et applications en psychiatrie
Français
978-2353270699
Jack RFoucher
article
303
Que manque-t’il à la rTMS pour devenir une thérapie ?
Encephale
2007
33
982-989
Repetitive trans-cranial magnetic stimulation (rTMS) can modulate cortical excitability. Consequently, it appears appealing for the treatment of some affections such as depression or hallucinations. There is already some proof that the concept is valid, but rTMS is slow in progressing in the therapeutic field as a true armamentum. Indeed its effects are of short duration and even inconstant from one patient to the next. These drawbacks depend on certain factors that we will discuss. Until now, there has been inadequate control of the stimulation site. It is possible that this site could vary on an individual basis. It seems logical to propose the use of functional imaging for such a purpose, but its use should be adapted to the symptom. Even after localizing the site, the coil has to be placed accurately. This could be facilitated by a neuronavigator. Stimulation protocols are currently defined by three parameters: the frequency modulating the cortical action either as a stimulation (>5 Hz) or an inhibition (<1 Hz), the intensity and the number of stimuli influencing, notably, the amplitude and duration of the effect. Unfortunately, the effect is inconstant in a given patient and paradoxical reactions have been observed in more than 15% of normal individuals. Improved reliability and amplification of the effect rely on the better control of other parameters: pattern of stimulation, pre and post-conditioning, state of the cortex during stimulation, associated medications, endogenous idiosyncratic factors and related pathology. We will review the current physiological literature to discuss the possible options that would constitute a rational basis for setting up more efficient protocols.
http://www.cercle-d-excellence-psy.org/fileadmin/cep_files/TMS_TTT_CEP.pdf
http://www.cercle-d-excellence-psy.org/fileadmin/cep_files/TMS_TTT_CEP.pdf
Français
Jack RFoucher
DavidLuck
SergeChassagnon
IsabelleOfferlin-Meyer
Bich-ThuyPham
article
12
Towards a robotic control of rTMS placement for therapeutic purpose. Asian Hospital & Healthcare Management
Asian Hospital & Healthcare Management
2007
http://www.asianhhm.com/Knowledge_bank/articles/transcranial_magnetic_stimulation.htm
http://www.asianhhm.com/Knowledge_bank/articles/transcranial_magnetic_stimulation.htm
Jack RFoucher
CyrilleLebossé
PierreRenaud
BernardBayle
Michelde Mathelin
article
302
La stimulation magnétique répétitive en thérapeutique neurologique et psychiatrique : des espoirs et des limites en commun
Epileptologie
2005
22
157-167
Les effets thérapeutiques de la Stimulation Magnétique Transcrânienne répétitive (SMTr) sont aujourd’hui explorés dans plusieurs pathologies psychiatriques et neurologiques lors desquelles cette technique semble capable de modifier le fonctionnement de structures ou de réseaux corticaux dysfonctionnels. Bien que son efficacité thérapeutique soit maintenant attestée par un nombre croissant de travaux dans certaines de ces pathologies, la SMTr est encore peu utilisée dans la pratique clinique et reste surtout étudiée dans le cadre de protocoles de recherche. Cela tient
pour une part à la courte durée de ses effets et au caractère inconstant de ceux-ci d’un sujet à l’autre, dans ses modalités d’administration actuelles. Après un rappel du principe général de fonctionnement de la SMTr nous
essayerons, au travers de la revue de la littérature concernant son application dans l’épilepsie et les hallucinations, de dégager certains facteurs susceptibles d’influencer l’effet obtenu. Nous envisagerons successivement : le choix du site de stimulation et sa localisation, les paramètres de stimulation (le nombre de stimuli délivrés, l’intensité et la fréquence de stimulation, son degré de focalisation), les médicaments associés, le patron de stimulation, et la question du conditionnement cortical pré-, per- et post-stimulation. Pour ces différents facteurs, nous proposerons des pistes de recherche qui pourraient permettre d’obtenir, dans le futur, une amélioration de l’efficacité de la SMTr et de faire accéder cette technique au rang de méthode thérapeutique à part entière.
http://www.epi.ch/_files/Artikel_Epileptologie/Vidailhet_4_05.pdf
http://www.epi.ch/_files/Artikel_Epileptologie/Vidailhet_4_05.pdf
Français
PierreVidailhet
Jack RFoucher
ValérieLauer
SergeChassagnon